Authors: Cristina Mesa-Vieira; Christiane Didden; Michael Schomaker; Johannes P. Mouton; Naomi Folb; Leigh L. van den Heuvel; Chiara Gastaldon; Morna Cornell; Mpho Tlali; Reshma Kassanjee; Oscar H. Franco; Soraya Seedat; Andreas D. Haas · Research
How Does PTSD Affect Heart Health in South Africa?
New research from South Africa reveals that PTSD increases the risk of major heart problems, highlighting the need for better cardiovascular care in PTSD patients.
Source: Mesa-Vieira, C., Didden, C., Schomaker, M., Mouton, J. P., Folb, N., van den Heuvel, L. L., Gastaldon, C., Cornell, M., Tlali, M., Kassanjee, R., Franco, O. H., Seedat, S., & Haas, A. D. (2024). Post-traumatic stress disorder as a risk factor for major adverse cardiovascular events: a cohort study of a South African medical insurance scheme. Epidemiology and Psychiatric Sciences, 33, e5, 1–9. https://doi.org/10.1017/S2045796024000052
What you need to know
- People with post-traumatic stress disorder (PTSD) in South Africa have a 16% higher risk of experiencing major heart problems compared to those without PTSD.
- This increased risk persists even after accounting for other mental health conditions and traditional heart disease risk factors.
- The findings highlight the importance of monitoring heart health in individuals diagnosed with PTSD, regardless of their exposure to war-related trauma.
Understanding PTSD and Its Prevalence
Post-traumatic stress disorder (PTSD) is a mental health condition that can develop after experiencing or witnessing a traumatic event. While often associated with combat veterans, PTSD can affect anyone who has been through a traumatic experience such as physical or sexual assault, natural disasters, accidents, or the sudden loss of a loved one.
In South Africa, the lifetime prevalence of PTSD is estimated at 2.3% of the general population. This may seem low, but it’s important to consider that many cases of PTSD go undiagnosed or untreated. The most common traumatic events in South Africa include the unexpected death of a loved one (affecting 39.2% of the population), physical violence (37.6%), accidents (31.9%), and witnessing traumatic events (29.5%).
The Link Between PTSD and Heart Health
Previous research, primarily conducted in the United States and focused on male veterans, has suggested a connection between PTSD and an increased risk of cardiovascular disease. However, this new study from South Africa provides valuable insights into how PTSD affects heart health in a more diverse population exposed to a wider range of traumatic experiences.
The researchers analyzed data from over one million South African medical insurance beneficiaries, following them for an average of 3 years. They looked at the occurrence of major adverse cardiovascular events (MACE), which include heart attacks, strokes, and hospitalizations for unstable angina or procedures to restore blood flow to the heart.
Key Findings
After adjusting for various factors including age, sex, HIV status, and other mental health conditions, the study found that people diagnosed with PTSD had a 16% higher risk of experiencing a major adverse cardiovascular event compared to those without PTSD.
This increased risk remained consistent even after accounting for traditional cardiovascular risk factors such as high blood pressure, diabetes, and high cholesterol. This suggests that PTSD itself may have a direct impact on heart health, independent of these other risk factors.
The study also found that the risk of cardiovascular events was highest in the first year after a PTSD diagnosis and gradually decreased over time. However, even after 8 years, people with PTSD still had a 14% higher risk of experiencing a major cardiovascular event compared to those without PTSD.
Why PTSD Might Affect Heart Health
There are several potential explanations for why PTSD could lead to an increased risk of heart problems:
Psychological and behavioral factors: PTSD can increase the risk of depression, substance misuse, and sleep disorders. These conditions, in turn, can lead to unhealthy lifestyle choices such as poor diet, lack of exercise, and smoking, which are all risk factors for heart disease.
Physiological changes: PTSD can affect various bodily systems that play a role in cardiovascular health. These include:
- Increased inflammation throughout the body
- Changes in the way the body regulates stress hormones
- Imbalances in the autonomic nervous system, which controls heart rate and blood pressure
These physiological changes can directly contribute to the development of heart disease over time.
Implications for Healthcare
This study has important implications for how we approach healthcare for people with PTSD:
Integrated care: The findings support the need for integrated care models that combine mental health services with physical healthcare. This approach can ensure that the cardiovascular health of PTSD patients is properly monitored and managed.
Early intervention: Given that the risk of cardiovascular events was highest in the first year after a PTSD diagnosis, early intervention and close monitoring of heart health during this period may be particularly important.
Long-term follow-up: Even though the risk decreased over time, it remained elevated even after 8 years. This suggests that long-term cardiovascular monitoring is necessary for PTSD patients.
Broadened focus: While much of the previous research on PTSD and heart health has focused on combat veterans, this study shows that the link exists in a broader population exposed to various types of trauma. Healthcare providers should be aware of this risk in all PTSD patients, not just those with combat-related trauma.
Limitations of the Study
While this research provides valuable insights, it’s important to note some limitations:
The study only included people with private medical insurance in South Africa, who represent about 15% of the population and generally have a higher socioeconomic status. The findings may not fully represent the entire South African population.
The study relied on medical insurance claims data, which may not capture all cases of PTSD or cardiovascular events, especially if people didn’t seek medical care.
The researchers didn’t have information on some important factors that could affect both PTSD and heart health, such as socioeconomic status, education level, or detailed information about lifestyle factors like diet and exercise.
The study couldn’t determine whether it was the traumatic event itself or the development of PTSD that led to the increased cardiovascular risk.
Conclusions
- PTSD is associated with a significantly increased risk of major cardiovascular events in South Africa, a finding that extends beyond the previously studied populations of combat veterans.
- This increased risk persists even after accounting for other mental health conditions and traditional cardiovascular risk factors, suggesting that PTSD itself may directly impact heart health.
- Healthcare providers should be aware of this increased cardiovascular risk in all patients with PTSD and consider implementing regular heart health monitoring as part of their care.
This research underscores the complex relationship between mental and physical health, highlighting the need for integrated care approaches that address both the psychological and physical health needs of individuals with PTSD. By recognizing and addressing this increased cardiovascular risk, healthcare providers can work towards improving overall health outcomes for people living with PTSD.