Authors: Omar Gammoh; Alaa A. A. Aljabali; Murtaza M. Tambuwala · Research

How Do Pain Medications Affect Mental Health in Refugee Women with Fibromyalgia?

Research examines the relationship between over-the-counter pain medications and mental health symptoms in Syrian refugee women with fibromyalgia.

Source: Gammoh, O., Aljabali, A.A.A., & Tambuwala, M.M. (2024). The crosstalk between subjective fibromyalgia, mental health symptoms and the use of over‑the‑counter analgesics in female Syrian refugees: a cross‑sectional web‑based study. Rheumatology International, 44, 715-723. https://doi.org/10.1007/s00296-023-05521-0

What you need to know

  • Over-the-counter pain medications may not effectively manage fibromyalgia symptoms in refugee women and could be associated with worse mental health outcomes
  • NSAIDs use was linked to more severe depression, insomnia, PTSD, and fibromyalgia symptoms
  • Proper diagnosis and treatment with appropriate centrally-acting medications may lead to better outcomes

Understanding the Connection Between Pain and Mental Health in Refugees

Living through war and displacement creates immense physical and psychological strain. For many refugee women, this trauma manifests as widespread body pain, sleep problems, and emotional distress - a condition known as fibromyalgia. While over-the-counter pain relievers might seem like an obvious solution, research suggests the relationship between pain medication use and mental health is more complex than it appears.

The Study: Examining Pain Management in Syrian Refugee Women

Researchers examined how different types of pain medications related to fibromyalgia and mental health symptoms among 291 Syrian refugee women living in Jordan. They looked at three main categories of pain relief:

  • Acetaminophen (like Tylenol)
  • NSAIDs (like ibuprofen)
  • Prescription medications that act on the brain’s pain processing

The women also completed assessments for fibromyalgia symptoms, depression, insomnia, and post-traumatic stress disorder (PTSD).

Key Findings: Not All Pain Relievers Are Equal

The results revealed some concerning patterns. Women using NSAIDs were:

  • 3 times more likely to have fibromyalgia symptoms
  • 2 times more likely to have severe depression
  • More likely to have higher PTSD scores

Those taking prescription centrally-acting medications showed:

  • Nearly 4 times higher likelihood of severe insomnia
  • Almost 3 times higher odds of severe depression
  • Higher PTSD scores

Interestingly, acetaminophen use wasn’t associated with any mental health outcomes.

Why the Connection?

The relationship between pain medications and mental health symptoms doesn’t necessarily mean the medications are causing these issues. Instead, it likely reflects that women with more severe fibromyalgia and emotional distress are more likely to seek stronger pain relief options.

Fibromyalgia itself involves complex changes in how the brain processes pain signals. This means that medications targeting only physical pain (like NSAIDs) may not address the root cause, leaving both pain and emotional symptoms inadequately treated.

What This Means for You

If you or someone you know is dealing with widespread pain and emotional distress after experiencing trauma:

  • Don’t rely solely on over-the-counter pain relievers
  • Seek proper medical evaluation for fibromyalgia
  • Consider that emotional and physical symptoms may need different treatments
  • Talk to healthcare providers about comprehensive treatment options
  • Be aware that mental health support may be as important as pain management

Conclusions

  • Proper fibromyalgia diagnosis and treatment requires more than just pain medication
  • Over-the-counter pain relievers alone may not provide adequate relief for refugee women with trauma-related pain
  • A comprehensive approach addressing both physical and mental health symptoms is likely to be most effective
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