Authors: Heike Weber; Adam X. Maihofer; Nenad Jaksic; Elma Feric Bojic; Sabina Kucukalic; Emina Sabic Dzananovic; Aferdita Goci Uka; Blerina Hoxha; Valdete Haxhibeqiri; Shpend Haxhibeqiri; Nermina Kravic; Mirnesa Muminovic Umihanic; Ana Cima Franc; Romana Babic; Marko Pavlovic; Alma Bravo Mehmedbasic; Branka Aukst-Margetic; Abdulah Kucukalic; Damir Marjanovic; Dragan Babic; Nada Bozina; Miro Jakovljevic; Osman Sinanovic; Esmina Avdibegović; Ferid Agani; Bodo Warrings; Katharina Domschke; Caroline M. Nievergelt; Jürgen Deckert; Alma Dzubur-Kulenovic; Angelika Erhardt · Research
How Do Genes, Trauma, and Coping Skills Affect PTSD Risk and Recovery?
Research reveals how genetic factors, trauma exposure, and coping strategies influence PTSD development and recovery
Source: Weber, H., Maihofer, A. X., Jaksic, N., Bojic, E. F., Kucukalic, S., Dzananovic, E. S., ... & Erhardt, A. (2022). Association of polygenic risk scores, traumatic life events and coping strategies with war‑related PTSD diagnosis and symptom severity in the South Eastern Europe (SEE)‑PTSD cohort. Journal of Neural Transmission, 129, 661-674.
What you need to know
- Both genetic factors and life experiences play a role in determining who develops PTSD after trauma
- The intensity of traumatic experiences has a stronger influence on PTSD than the number of traumatic events
- How people cope with trauma significantly affects their risk of developing PTSD and their recovery
Understanding PTSD Risk Factors
Imagine two soldiers who experience the same traumatic event in combat. One develops post-traumatic stress disorder (PTSD), while the other processes the experience without lasting psychological effects. Why do people respond differently to trauma? This question has puzzled mental health researchers for decades.
A groundbreaking study of war survivors from South Eastern Europe offers new insights into this mystery by examining how genes, trauma exposure, and coping strategies work together to influence who develops PTSD and how severe their symptoms become.
The Role of Genetics
While previous research established that PTSD runs in families, this study helps clarify the genetic component. The researchers found a small but significant genetic risk for developing PTSD by analyzing variations in DNA sequences across thousands of genes.
However, genetic risk played a relatively minor role compared to other factors. This suggests that while our genes may make us somewhat more susceptible to PTSD, they don’t determine our destiny.
The Impact of Trauma Exposure
The intensity of traumatic experiences emerged as one of the strongest predictors of PTSD. People who experienced more severe trauma were significantly more likely to develop PTSD compared to those who experienced milder trauma.
Interestingly, it wasn’t just the number of traumatic events that mattered, but how intense those experiences were. This suggests that a single extremely traumatic event could have more impact than multiple less severe traumas.
The Power of Coping Strategies
How people cope with trauma proved to be another crucial factor. The study identified two main types of coping:
- Positive coping strategies: Like seeking social support, problem-solving, and finding meaning in experiences
- Negative coping strategies: Such as avoiding reminders of trauma, self-blame, and emotional withdrawal
People who used more positive coping strategies generally had less severe PTSD symptoms, while those who relied on negative coping strategies tended to have worse outcomes.
What This Means for You
These findings have important implications for PTSD prevention and treatment:
- If you’ve experienced trauma, remember that your genes don’t determine your destiny
- The severity of your trauma matters more than the number of traumatic events
- Learning positive coping strategies can help reduce PTSD risk and aid recovery
- Early intervention after severe trauma may help prevent chronic PTSD
- Support systems and professional help can teach better coping strategies
Conclusions
- PTSD develops through a complex interaction of genetic predisposition, trauma exposure, and coping strategies
- While we can’t change our genes or past traumas, we can develop better coping skills
- Professional help and support systems play vital roles in PTSD prevention and recovery